Representative Publications
*Corresponding authors
#Contributed equally
*Corresponding authors
#Contributed equally
Bio-Inspired Microreactors Continuously Synthesize Glucose Precursor from CO2 with an Energy Conversion Efficiency 3.3 Times of Rice
Zhu YJ, Xie FJ, Wun TCK, Li KC, Lin H, Tsoi CC, Jia HP, Chai Y, Zhao Q, Lo BTW, Leu SY, Jia YW, Ren KN*, Zhang XM* Advanced Science. 2024. doi: 10.1002/advs.202305629. |
ZSWIM4 regulates embryonic patterning and BMP signaling by promoting nuclear Smad1 degradation
Wang CD, Liu ZR, Zeng YL, Zhou LJ, Long Q, Hassan I UI, Zhang YL, Qi XF, Cai DQ, Mao BY, Lu G, Sun JM, Yao YG, Deng Y, Zhao Q, Feng B, Zhou Q, Chan WY, Zhao H* EMBO Reports. 2024. doi: 10.1038/s44319-023-00046-w. |
Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression
Leeman-Neill RJ, Song D, Bizarro J, Wacheul L, Rothschild G, Singh S, Yang Y, Sarode AY, Gollapalli K, Wu LJ, Zhang WW, Chen YY, Lauring MC, Whisenant DE, Bhavsar S, Lim JH, Swerdlow SH, Bhagat G, Zhao Q, Berchowitz LE, Lafontaine DLJ, Wang JG*, Basu U* Nature Genetics. 2023. doi: 10.1038/s41588-023-01561-1. |
Broad-spectrum kinome profiling identifies CDK6 upregulation as a driver of lenvatinib resistance in hepatocellular carcinoma
Leung CON, Yang Y, Leung RW, So KK, Guo HJ, Lei MM, Muliawan GK, Gao Y, Yu QQ, Yun JP, Ma S, Zhao Q*, Lee TK* Nature Communications. 2023. doi: 10.1038/s41467-023-42360-w. |
Ynamide Coupling Reagent for the Chemical Cross-Linking of Proteins in Live Cells
Li SR, Zhu CJ, Zhao Q, Zhang ZM*, Sun PH*, Li ZQ* ACS Chemical Biology. 2023. doi: 10.1021/acschembio.3c00149. |
The Human pre-replication complex is an open complex
Li J#, Dong JQ#, Wang WT#, Yu DQ#, Fan XY, Hui YC, Lee SK, Lam WH, Alary N, Yang Y, Zhao Q, Chen CL*, Tye BK*, Dang SY*, Zhai YL* Cell. 2023. doi: 10.1016/j.cell.2022.12.008. |
An optimized proteomics approach reveals novel alternative proteins in mouse liver development
Yang Y#, Wang HW#, Zhang YL, Chen L, Chen GL, Bao ZS, Yang Y, Xie Z, Zhao Q* Molecular & Cellular Proteomics. 2022. doi: 10.1016/j.mcpro.2022.100480. |
Integrated Mass Spectrometry Reveals Celastrol As a Novel Catechol-O-methyltransferase Inhibitor
Guo HJ#, Yang Y#, Zhang Q#, Deng JR, Yang Y, Li SQ, So PK, Lam TC, Wong MK, Zhao Q* ACS Chemical Biology. 2022. doi: 10.1021/acschembio.2c00011. |
Deficiency of ribosomal proteins reshapes the transcriptional and translational landscape in human cells
Luan YZ, Tang N, Yang JQ, Liu ST, Cheng CC, Wang Y, Chen CY, Guo YN, Wang HW, Zhao WX, Zhao Q, Li W, Xiang MQ, Ju R*, Xie Z* Nucleic Acids Research. 2022, gkac053. doi: https://doi.org/10.1093/nar/gkac053. |
Two-photon fluorescent turn-on probes for highly efficient detection and profiling of thiols in live cells and tissues
Shen CZ#, Zhang DT#, Xu F#, Yang Y#, Tan Y, Zhao Q*, Li L, Ding K, Li ZQ* Biological Chemistry. 2021;403(4):445-451. |
The Small Open Reading Frame‐Encoded Peptides: Advances in Methodologies and Functional Studies
Chen L, Yang Y, Zhang YL, Li KC, Cai HM, Wang HW, Zhao Q* ChemBioChem. 2021. doi: 10.1002/cbic.202100534. |
An integrated approach for discovering non-canonical MHC-I peptides encoded by small open reading frames
Chen L, Zhang YL, Yang Y, Yang Y, Li HH, Dong X, Wang HW, Xie Z, Zhao Q* Journal of the American Society for Mass Spectrometry. 2021;32(9):2346-2357. |
Tissue- and stage-specific landscape of the mouse translatome
Wang HW#, Wang Y#, Yang JQ#, Zhao Q#, Tang N, Chen CY, Li HH, Cheng CC, Xie MZ, Yang Y, Xie Z* Nucleic Acids Research. 2021;49(11):6165-80. |
EPHB2 activates β-catenin to enhance cancer stem cell properties and drive sorafenib resistance in hepatocellular carcinoma
Leung HW, Leung CON, Lau EY, Chung KPS, Mok EH, Lei MML, Leung RWH, Tong M, Keng V, Ma C, Zhao Q, Ng IOL, Ma S*, Lee KW* Cancer Research. 2021;81(12):3229-40. |
High-pH reversed-phase fractionated neural retina proteome of normal growing C57BL/6 mouse
Sze YH, Zhao Q, Cheung JKW, Li KK, Tse DYY, To CH, Lam TC* Scientific Data. 2021;8(27). |
Integrative Chemical Proteomics-Metabolomics Approach Reveals Acaca/Acacb as Direct Molecular Targets of PFOA
Shao XJ, Ji FF, Wang YW, Zhu L, Zhang Z, Du XB, Chung ACK, Hong YJ, Zhao Q*, Cai ZW* Analytical Chemistry. 2018;90(18):11092-11098. |
Locally translated mTOR controls axonal local translation in nerve injury
Terenzio M, Koley S, Samra N, Rishal I, Zhao Q, Sahoo PK, Urisman A, Marvaldi L, Oses-Prieto JA, Forester C, Gomes C, Kalinski AL, Di Pizio A, Doron-Mandel E, Perry RBT, Koppel I, Twiss JL, Burlingame AL, Fainzilber M* Science. 2018;359(6382):1416-1421. |
Revealing nascent proteomics in signaling pathways and cell differentiation
Forester CM#, Zhao Q#, Phillips NJ, Urisman A, Chalkley RJ, Oses-Prieto JA, Zhang L, Ruggero D*, Burlingame AL* Proceedings of the National Academy of Sciences U S A. 2018;115(10):2353-8. |
Broad-spectrum kinase profiling in live cells with lysine-targeted sulfonyl fluoride probes
Zhao Q#, Ouyang XH#, Wan XB, Gajiwala KS, Kath JC, Jones LH, Burlingame AL, Taunton J* Journal of the American Chemical Society. 2017;139(2):680-5. |
Comprehensive Analysis of Acylcarnitine Species in db/db Mouse Using a Novel Method of High-Resolution Parallel Reaction Monitoring Reveals Widespread Metabolic Dysfunction Induced by Diabetes
Xiang L, Wei JT, Tian XY, Wang B, Chan W, Li SF, Tang Z, Zhang HS, Cheang WS, Zhao Q, Zhao HZ, Yang ZY, Hong YJ, Huang Y*, Cai ZW* Analytical Chemistry. 2017;89(19):10368-75. |
Natural products triptolide, celastrol, and withaferin A inhibit the chaperone activity of peroxiredoxin I
Zhao Q, Ding Y, Deng ZS, Lee OY, Gao P, Chen P, Rose RJ, Zhao H, Zhang ZH, Tao XP, Heck AJR, Kao R, Yang D* Chemical Science. 2015;6(7):4124-30. 6. |
A chemical probe for lysine malonylation
Bao X#, Zhao Q#, Yang TP, Fung YME*, Li XD* Angewandte Chemie - International Edition. 2013;52(18):4883-6. |